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| Dataset construction | |||||||
|---|---|---|---|---|---|---|---|
| Primary set (lectin sequences from PIR/PRF/PDB/DDBJ/EMBL/Genbank/SwissProt) | 7865 | ||||||
| Filtered set | |||||||
| Length criteria | 6820 |
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Sequence redundancy |
3824 |
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| Manual inspection of annotation | 3141 | ||||||
| Final set (Lectindb) | 3087 |
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| Number of animals in the final set | 237 |
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| Domain Annotation | |||||||
|---|---|---|---|---|---|---|---|
Total number of domains in AnimalLectindb |
17455/15634 |
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Total/unique domains identified from |
CDD |
COG |
KOG |
PFAM |
SMART |
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Total number of domains: sum of unique domains in all domain databases |
902 (contains 2428 lectin domains) |
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Unique domains from total number of domains |
574 ( contains 25 lectin domains) |
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Number of lectin sequences with multiple domains |
2236 |
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| Structural Annotation | |||
|---|---|---|---|
| Lectins whose structure is available through PDB | 61 |
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| Lectins whose structure can be built by homology modeling | 2076 |
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| Lectins or domains in lectin containing proteins, whose structure can be predicted (in part or full) by fold recognition | 766 |
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| Lectin containing proteins with no structural annotation | 184 |
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| Distribution of lectin domains across various folds | |
|---|---|
Annexin |
276 |
Beta prism I |
3 |
Beta prism II |
7 |
Beta trefoil |
28 |
Concanavalin A |
307 |
C-type lectin |
1021 |
Knottins |
140 |
P-domain of calnexin/calreticulin |
15 |
Distribution of other domains co-occurring with lectins |
269 |
| Functional Annotation | |||
|---|---|---|---|
| Number of lectins with annotation from | |||
| InterPro | 1428 |
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GO |
1208 |
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PRINTS |
591 |
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PRODOM |
310 |
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PROSITE |
1235 |
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Number of plants with known carbohydrate specificity |
677 |
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Number of lectins predicted to have a signal peptide |
1115 |
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OMIM |
285 |
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